Long term outcome of medical and surgical co-management of craniospinal aspergillosis in an immunocompromised patient

Publication date: Available online 29 November 2016
Source:Medical Mycology Case Reports
Author(s): TS. Dipu, B. Sabarish, Anil Kumar, M.R. Bindhu, Ashok Pillai, Vidya P. Menon
35yr old steroid dependent lady with Pulmonary TB underwent debridement of epidural abscess & posterior stabilization for paraparesis. With histopathology and cultures showing Aspergillus fumigatus, voricanozole was started. By the fourth week, she developed persistent fever, and altered mental status. Brain MRI and CSF study including multiplex PCR evaluation confirmed cerebral aspergillosis. Voricanozole was changed to intravenous lipid complex Amphotericin B to achieve sustained clinical and radiological response after six months of therapy.



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